perinatal mortality in rural burkina faso a prospective community-based cohort study围产期死亡率在布基纳法索农村未来的以社区为基础的队列研究.pdfVIP

Diallo et al. BMC Pregnancy and Childbirth 2010, 10:45 /1471-2393/10/45 RESEARCH ARTICLE Open Access Perinatal mortality in rural Burkina Faso: a prospective community-based cohort study 1,2* 1 1 2,3 4 Abdoulaye Hama Diallo , Nicolas Meda , Emmanuel Zabsonré , Halvor Sommerfelt , Simon Cousens , 2 Thorkild Tylleskär , the PROMISE-EBF study group Abstract Background: There is a scarcity of reliable data on perinatal mortality (PNM) in Sub-Saharan Africa. The PROMISE- EBF trial, during which we promoted exclusive breastfeeding, gave us the opportunity to describe the epidemiology of PNM in Banfora Health District, South-West in Burkina Faso. Study objectives: To measure the perinatal mortality rate (PNMR) in the PROMISE-EBF cohort in Banfora Health District and to identify potential risk factors for perinatal death. Methods: We used data collected prospectively during the PROMISE-EBF-trial to estimate the stillbirth rate (SBR) and early neonatal mortality rate (ENMR). We used binomial regression with generalized estimating equations to identify potential risk factors for perinatal death. Results: 895 pregnant women were enrolled for data collection in the EBF trial and followed-up to 7 days after birth. The PNMR, the SBR and the ENMR, were 79 per 1000 (95% CI: 59-99), 54 per 1000 (95% CI: 38-69) and 27 per 1000 (95% CI: 9-44), respectively. In a multivariable analysis, nulliparous women (RR = 2.90, 95% CI: 1.6-5.0), primiparae mothers (RR = 2.20, 95% CI: 1.2-3.9), twins (RR = 4.0, 95% CI: 2.3-6.9) and giving birth during the dry season (RR = 2.1 95% CI: 1.3-3.3) were factors associated with increased risk of perinatal death. There was no eviden