phenolics occurrence and immunochemical detection in environment and food酚醛树脂发生和免疫化学检测在环境和食品.pdfVIP

Molecules 2009, 14, 439-473; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review Phenolics: Occurrence and Immunochemical Detection in Environment and Food Eline P. Meulenberg * ELTI Support VOF, Drieskensacker 12-10, 6546 MH Nijmegen, The Netherlands * Author to whom correspondence should be addressed. E-mail: E.Meulenberg@eltisupport.nl Received: 30 November 2008; in revised form: 6 January 2008 / Accepted: 12 January 2009 / Published: 19 January 2009 Abstract: Phenolic compounds may be of natural or anthropogenic origin and be present in the environment as well as in food. They comprise a large and diverse group of compounds that may be either beneficial or harmful for consumers. In this review first a non-exhausting overview of interesting phenolics is given, in particular with regards to their presence in environment and food. For some of these compounds, beneficial, toxicological and/or optionally endocrine disrupting activities will be presented. Further, immunochemical detection and/or isolation methods developed will be discussed, including advantages and disadvantages thereof in comparison with conventional analytical methods such as HPLC, GC, MS. A short overview of new sensor-like methods will also be included for present and future application. Keywords: Phenolics; Environment; Food; Immunochemical detection; Isolation; Endocrine activity. Introduc