planning for translational research in genomics在基因组学计划转化研究.pdfVIP

Correspondence PPllaannnniinngg ffoorr ttrraannssllaattiioonnaall rreesseeaarrcchh iinn ggeennoommiiccss Naomi Hawkins, Jantina de Vries, Paula Boddington, Jane Kaye and Catherine Heeney Address: The Ethox Centre, Department of Public Health, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK Correspondence: Naomi Hawkins. Email: naomi.hawkins@ethox.ox.ac.uk Published: 29 September 2009 Received: 29 May 2009 Revised: 26 June 2009 Genome Medicine 2009, 11::87 (doi:10.1186/gm87) Accepted: 11 September 2009 The electronic version of this article is the complete one and can be found online at /content/1/9/87 © 2009 Hawkins et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. AAbbssttrraacctt Translation of research findings into clinical practice is an important aspect of medical progress. Even for the early stages of genomics, research aiming to deepen understandings of underlying mechanisms of disease, questions about the ways in which such research ultimately can be useful in medical treatment and public health are of key importance. Whilst some research data may not apparently lend themselves to immediate clinical benefit, being aware of the issues surrounding translation at an early stage can enhance the delivery of the research to the clinic if a medical application is later found. When simple steps are taken dur