preparation of a nanosized as2o3mn0.5zn0.5fe2o4 complex and its anti-tumor effect on hepatocellular carcinoma cells制备的纳米尺度的as2o3mn0.5zn0.5fe2o4复杂及其对肝癌细胞的抗肿瘤效应.pdfVIP

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preparation of a nanosized as2o3mn0.5zn0.5fe2o4 complex and its anti-tumor effect on hepatocellular carcinoma cells制备的纳米尺度的as2o3mn0.5zn0.5fe2o4复杂及其对肝癌细胞的抗肿瘤效应.pdf

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preparation of a nanosized as2o3mn0.5zn0.5fe2o4 complex and its anti-tumor effect on hepatocellular carcinoma cells制备的纳米尺度的as2o3mn0.5zn0.5fe2o4复杂及其对肝癌细胞的抗肿瘤效应

Sensors 2009, 9, 7058-7068; doi:10.3390/ OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article Preparation of a Nanosized As O /Mn Zn Fe O Complex and 2 3 0.5 0.5 2 4 Its Anti-Tumor Effect on Hepatocellular Carcinoma Cells Jia Zhang 1,2 and Dongsheng Zhang 1,2,* 1 School of Basic Medical Science, Southeast University, Nanjing 210009, China 2 School of Clinical Medical Science, Southeast University, Nanjing 210009, China; E-Mail: happyzhj2008@ * Author to whom correspondence should be addressed; E-Mail: b7712900@; Tel.: +86-25-832 725 02 Received: 25 June 2009; in revised form: 17 August 2009 / Accepted: 3 September 2009 / Published: 4 September 2009 Abstract: Manganese-zinc-ferrite nanoparticles (Mn Zn Fe O , MZF-NPs) prepared by 0.5 0.5 2 4 an improved co-precipitation method and were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD) and energy dispersive spectrometry (EDS). Then thermodynamic testing of various doses of MZF-NPs was performed in vitro. The cytotoxicity of the Mn Zn Fe O nanoparticles in vitro was tested by the MTT assay. A 0.5 0.5 2 4 nanosized As O /Mn Zn Fe O complex was made by