prevalence and risk factors of hepatitis b and c virus infections among the general population and blood donors in morocco患病率和b和c型肝炎病毒感染的危险因素在一般人群和献血者在摩洛哥.pdfVIP

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prevalence and risk factors of hepatitis b and c virus infections among the general population and blood donors in morocco患病率和b和c型肝炎病毒感染的危险因素在一般人群和献血者在摩洛哥.pdf

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prevalence and risk factors of hepatitis b and c virus infections among the general population and blood donors in morocco患病率和b和c型肝炎病毒感染的危险因素在一般人群和献血者在摩洛哥

Baha et al. BMC Public Health 2013, 13:50 /1471-2458/13/50 RESEARCH ARTICLE Open Access Prevalence and risk factors of hepatitis B and C virus infections among the general population and blood donors in Morocco 1,2 1 1 3,4 3 Warda Baha , Abderrahim Foullous , Noureddine Dersi , Thierry Paluku They-they , Khadija El alaoui , 3 4 1 1 2 Nadia Nourichafi , Bouchra Oukkache , Fatiha Lazar , Soumaya Benjelloun , My Mustapha Ennaji , Abdelouhad Elmalki1, Hassan Mifdal3 and Abdelouaheb Bennani1* Abstract Background: Viral hepatitis is a serious public health problem affecting billions of people globally. Limited information is available on this issue in Morocco. This cross-sectional study was undertaken with the aim of determining the seroprevalence and risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) among the general population and among blood donors. Methods: Blood samples from volunteers, have been screened with ELISA tests for detecting the hepatitis-B surface antigen (HBsAg) and anti-HCV. Within the seroreactive patients for HCV in the general population, RT-PCR was performed by the Cobas Ampliprep/Cobas Amplicor. Results: HCV and HBV-seropositivity was documented in 1.58% and 1.81% out of 41269 and 23578 participants respectively from the general population. Two patients were found to be co-infected. HCV-RNA was detected by PCR in 70.9% of the 195 anti-HCV positive subjects. The anti-HCV prevalence was not different among males and females (P = 0.3). It increased with age; the highest prevalence was observed among subjects with 50 years old (3.12%). Vari