prospective validation of the “rhino conjunctivitis allergy-control-score？” (rc-acs？)潜在的验证u201c犀牛结膜炎allergy-control-score u201d(rc-acs ).pdfVIP

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prospective validation of the “rhino conjunctivitis allergy-control-score？” (rc-acs？)潜在的验证u201c犀牛结膜炎allergy-control-score u201d(rc-acs ).pdf

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prospective validation of the “rhino conjunctivitis allergy-control-score？” (rc-acs？)潜在的验证u201c犀牛结膜炎allergy-control-score u201d(rc-acs )

Häfner et al. Clinical and Translational Allergy 2012, 2:17 /content/2/1/17 RESEARCH Open Access Prospective validation of the “rhino conjunctivitis allergy-control-SCORE© © ” (RC-ACS ) 1* 2 2 2 1 1 1 Dietrich Häfner , Kristian Reich , Ina Zschocke , Annett Lotzin , Hanns Meyer , Jens Kettner and Annemie Narkus Abstract Background: Recently we reported the validation of the “Allergy-Control-SCORE© (ACS)” which assesses symptom severity as well as medication use on three dimensions lung, nose and eyes. The aim of this study was to test the validity of the score for eyes and nose. Methods: One-hundred-twenty-one consenting subjects (age 19-65y), including 81 patients with allergic rhino-conjunctivitis (RC) and 40 healthy controls, participated in the study. Patients rated daily nasal and eye symptoms using a 4-point scale (none, mild, moderate, and severe) and their use of anti-symptomatic medication. Validation criteria were pollen counts in the course of the study period. Discrimination capacity was analyzed by © © comparing the rhino-conjunctivitis Allergy-Control-SCORE (RC-ACS ) values of allergic patients and healthy controls. Convergent reliability was assessed by correlating RC-ACS© values with the global severity of allergy, the quality of life, and the allergy-related medical consultations. Retest reliability was assessed by the correlation of the repeated measured RC-ACS© scores during each of two consecutive weeks. Results: C