原创力文档prostaglandin e2 synthesis in cartilage explants under compression mpges-1 is a mechanosensitive gene前列腺素e2合成软骨外植体在压缩mpges-1 mechanosensitive基因.pdfVIP
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prostaglandin e2 synthesis in cartilage explants under compression mpges-1 is a mechanosensitive gene前列腺素e2合成软骨外植体在压缩mpges-1 mechanosensitive基因
Available online /content/8/4/R135
Vol 8 No 4 Open Access
Research article
Prostaglandin E2 synthesis in cartilage explants under
compression: mPGES-1 is a mechanosensitive gene
1 1,2 1 1 3
Marjolaine Gosset , Francis Berenbaum , Arlette Levy , Audrey Pigenet , Sylvie Thirion , Jean-
Louis Saffar4 and Claire Jacques1
1UMR 7079 CNRS, Physiology and Physiopathology Laboratory, University Paris 6, quai St-Bernard, Paris, 75252 Cedex 5, France
2Department of Rheumatology, UFR Pierre et Marie Curie, Saint-Antoine Hospital, 75012 Paris, France
3CNE Neuroendocrine Cellular Interactions, UMR CNRS 6544, Mediterranean University, Faculty of Medecine, 13916 Marseille Cedex 20, France
4Laboratory on Oro-facial Repair and Replannings EA 2496, University Paris Descartes, Faculty of Odontology, 92120 Montrouge, France
Corresponding author: Francis Berenbaum, francis.berenbaum@sat.ap-hop-paris.fr
Received: 21 Feb 2006 Revisions requested: 6 Apr 2006 Revisions received: 5 Jul 2006 Accepted: 27 Jul 2006 Published: 27 Jul 2006
Arthritis Research Therapy 2006, 8:R135 (doi:10.1186/ar2024)
This article is online at: /content/8/4/R135
© 2006 Gosset et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Knee osteoarthritis (OA) results, at least in part, from (enzyme immunoassay), mRNA and proteins were extracted
ove
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