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p-value based visualization of codon usage data基于假定值的密码子使用情况数据的可视化
Algorithms for Molecular Biology BioMed Central
Research Open Access
P-value based visualization of codon usage data
1 2 3
Peter Meinicke* , Thomas Brodag , Wolfgang Florian Fricke and
Stephan Waack2
1
Address: Abteilung Bioinformatik, Institut für Mikrobiologie und Genetik, Georg-August-Universität Göttingen, Goldschmidtstr. 1, 37077
Göttingen, Germany, 2Institut für Numerische und Angewandte Mathematik, Universität Göttingen, Lotzestr. 16, 37083 Göttingen, Germany and
3Göttingen Genomics Laboratory, Universität Göttingen, Grisebachstr. 8, 37077 Göttingen, Germany
Email: Peter Meinicke* - pmeinic@gwdg.de; Thomas Brodag - Thomas.Brodag@T-Online.de; Wolfgang Florian Fricke - wfricke@gwdg.de;
Stephan Waack - waack@cs.uni-goettingen.de
* Corresponding author
Published: 29 June 2006 Received: 13 March 2006
Accepted: 29 June 2006
Algorithms for Molecular Biology 2006, 1:10 doi:10.1186/1748-7188-1-10
This article is available from: /content/1/1/10
© 2006 Meinicke et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Two important and not yet solved problems in bacterial genome research are the identification of
horizontally transferred genes and the prediction of gene expression levels. Both problems can be
addressed by multivariate analysis of codon usage data.
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