recent advances in microflow photochemistry微流光化学的最新进展.pdfVIP

Molecules 2011, 16, 7522-7550; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review Recent Advances in Microflow Photochemistry Michael Oelgemöller 1,* and Oksana Shvydkiv 2 1 School of Pharmacy and Molecular Sciences, James Cook University, Townsville, QLD 4811, Australia 2 School of Chemical Sciences, Dublin City University, Dublin 9, Ireland * Author to whom correspondence should be addressed; E-Mail: michael.oelgemoeller@.au; Tel.: +61-7-4781-4543; Fax: +61-7-4781-6078. Received: 12 August 2011; in revised form: 31 August 2011 / Accepted: 31 August 2011 / Published: 5 September 2011 Abstract: This review summarizes recent advances in microflow photochemical technologies and transformations. The portfolio of reactions comprises homogeneous and heterogeneous types, among them photoadditions, photorearrangements, photoreductions, photodecarboxylations, photooxygenations and photochlorinations. While microflow photochemistry is most commonly employed as a micro-scale synthesis tool, scale-up and technical production processes have already been developed. Keywords: photochemistry; microflow chemistry; microreactor 1. Introduction Synthetic organic photochemistry uses light as an energy source to initiate chemical transformations. Following this approach, a large variety of photoreactions with high selectivity, chemical yields and photon efficiencies have been developed [1-3]. Due to its easy gen