recombinant activated factor vii as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy subgroup analysis from two randomized trials重组激活因子vii作为辅助治疗出血控制严重创伤患者凝血障碍亚组分析从两个随机试验.pdfVIP
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recombinant activated factor vii as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy subgroup analysis from two randomized trials重组激活因子vii作为辅助治疗出血控制严重创伤患者凝血障碍亚组分析从两个随机试验
Available online /content/10/6/R178
Vol 10 No 6 Open Access
Research
Recombinant activated factor VII as an adjunctive therapy for
bleeding control in severe trauma patients with coagulopathy:
subgroup analysis from two randomized trials
1 2 3 4 5 6
Sandro B Rizoli , Kenneth D Boffard , Bruno Riou , Brian Warren , Philip Iau , Yoram Kluger ,
7 8
Rolf Rossaint , Michael Tillinger and the NovoSeven® Trauma Study Group
1Department of Surgery and Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave., Suite H1-71,
Toronto, Ontario, M4N 3M5 Canada
2Department of Surgery, Johannesburg Hospital, University of the Witwatersrand, 17 Pallinghurst Road, Parktown, ZA – Johannesburg 2193, South
Africa
3Departments of Emergency Medicine and Surgery and Anesthesiology and Critical Care, Hôpital Pitié Salpêtrière, Assistance Publique-Hôpitaux de
Paris, Université Pierre et Marie Curie, 4 Place Jussieu, 75005, Paris, France
4Department of Surgery, Tygerberg Hospital, University of Stellenboch, Fransie van Zyl Avenue, Tygerberg, Bellville 7530 Cape Town, South Africa
5Department of Surgery, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074
6Department of General Surgery B, Rambam Medical Centre, 66 Jabotinsky St., Petach Tikvah Bat-Galim, Haifa, 49100, Israel
7Department of Anesthesiology, University Clinics, Pauwelsstr. 30, 52057 Aachen, Germany
8Medical and Science Department, Novo Nordisk A/S, Novo Alle 2880 Bagsværd, Denmark
Corresponding author: Sandro B Rizoli, sandro.rizoli@sw.ca
Received: 1
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