原创力文档response of tibialis anterior tendon to a chronic exposure of stretch-shortening cycles age effects回应的胫骨前肌腱stretch-shortening周期的慢性暴露年龄的影响.pdfVIP
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response of tibialis anterior tendon to a chronic exposure of stretch-shortening cycles age effects回应的胫骨前肌腱stretch-shortening周期的慢性暴露年龄的影响
BioMedical Engineering OnLine BioMed Central
Research Open Access
Response of tibialis anterior tendon to a chronic exposure of
stretch-shortening cycles: age effects
James S Ensey, Melinda S Hollander, John Z Wu, Michael L Kashon,
Brent B Baker and Robert G Cutlip*
Address: National Institute for Occupational Safety and Health (NIOSH), Health Effects Laboratory Division, Morgantown, West Virginia 26505,
USA
Email: James S Ensey - jensey@; Melinda S Hollander - mindysue1@; John Z Wu - jwu@;
Michael L Kashon - mkashon@; Brent B Baker - bbaker@; Robert G Cutlip* - rgc8@
* Corresponding author
Published: 29 June 2009 Received: 16 December 2008
Accepted: 29 June 2009
BioMedical Engineering OnLine 2009, 8:12 doi:10.1186/1475-925X-8-12
This article is available from: /content/8/1/12
© 2009 Ensey et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The purpose of the current study was to investigate the effects of aging on tendon
response to repetitive exposures of stretch-shortening cycles (SSCs).
Methods: The left hind limb from young (3 mo, N = 4) and old (30 mo, N = 9) male Fisher 344 ×
Brown Norway rats were exposed to 80 maximal SSCs (60 deg/s, 50 deg range of motion) 3x/week
for 4.5 weeks in vivo. After the last exposure, tendons from t
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