restricted maximum likelihood to estimate variance components for mixed models with two random factors限制最大似然估计方差组件混合模型与两个随机因素.pdfVIP

Restricted Maximum Likelihood to estimate variance components for mixed models with two random factors Karin MEYER lnstitute of Animal Genetics, University of Edinburgh West Mains Road, Edinburgh EH9 3JN, Scotland U. K. and Genetic Improvement of Livestock, Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario N1G 2W], Canada Summary A Restricted Maximum Likelihood procedure is described to estimate variance components for a univariate mixed model with two random factors. An EM-type algorithm is presented with a reparameterisation to speed up the rate of convergence. Computing strategies are outlined for models common to the analysis of animal breeding data, allowing for both a nested and a cross- classified design of the 2 random factors. Two special cases are considered : firstly, the total number of levels of fixed effects is small compared to the number of levels of both random factors ; secondly, one fixed effect with a large number of levels is to be fitted in addition to other fixed effects with few levels. A small numerical example is given to illustrate details. Key words : Restricted Maximum Likelihood, variance component estimation, nested design, full sib family structure. Résumé Estimation des composantes de la variance par le Maximum de Vraisemblance Restreint dans un modèle mixte à deux facteurs aléatoires Une méthode d’estimation des composantes de la variance par le Maximum de Vraisemblance Restreint est décrite dans le cas d’un modèle mixte à une seule variable avec 2 facteurs aléatoires. Un algorithme de calcul du ty