原创力文档renal alterations in feline immunodeficiency virus (fiv)-infected cats a natural model of lentivirus-induced renal disease changes肾功能改变猫免疫缺陷病毒(fip)来华的猫的自然模型lentivirus-induced肾脏疾病的变化.pdfVIP
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renal alterations in feline immunodeficiency virus (fiv)-infected cats a natural model of lentivirus-induced renal disease changes肾功能改变猫免疫缺陷病毒(fip)来华的猫的自然模型lentivirus-induced肾脏疾病的变化
Viruses 2012, 4, 1372-1389; doi:10.3390/v4091372
OPEN ACCESS
viruses
ISSN 1999-4915
/journal/viruses
Article
Renal Alterations in Feline Immunodeficiency Virus
(FIV)-Infected Cats: A Natural Model of Lentivirus-Induced
Renal Disease Changes
Alessandro Poli 1, Natasa Tozon 2, Grazia Guidi 3 and Mauro Pistello 4,*
1 Department of Animal Pathology, Prophylaxis and Food Hygiene, Veterinary Faculty,
University of Pisa, Viale delle Piagge 2, Pisa 56124, Italy; E-Mail: apoli@vet.unipi.it
2 Clinic for Small Animal Medicine and Surgery, Veterinary Faculty, University of Ljubljana,
Gerbičeva 60, Ljubljana 1000, Slovenia; E-Mail: Natasa.Tozon@vf.uni-lj.si
3 Department of Veterinary Clinic, Veterinary Faculty, University of Pisa, Via Livornese,
San Piero a Grado, Pisa 56122, Italy; E-Mail: guidi@vet.unipi.it
4 Department of Experimental Pathology, University of Pisa, Via S. Zeno, 35/39,
Pisa 56127, Italy
* Author to whom correspondence should be addressed; E-Mail: mauro.pistello@med.unipi.it;
Tel.: +39-050-221-3781; Fax: +39-050-221-3524.
Received: 18 July 2012; in revised form: 15 August 2012 / Accepted: 16 August 2012 /
Published: 27 August 2012
Abstract: Human immunodeficiency virus (HIV) is associated with several renal
syndromes including acute and chronic renal failures, but the underlying pathogenic
mechanisms are unclear. HIV and feline immunodeficiency virus (FIV) share numerous
biological and pathological features, including renal alterations. We inve
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