review of zero-d and 1-d models of blood flow in the cardiovascular system回顾zero-d和心血管系统血液流动的一维模型.pdf

Shi et al. BioMedical Engineering OnLine 2011, 10:33 /content/10/1/33 REVIEW Open Access Review of Zero-D and 1-D Models of Blood Flow in the Cardiovascular System * Yubing Shi, Patricia Lawford and Rodney Hose * Correspondence: d.r.hose@shef. Abstract ac.uk Medical Physics Group, Background: Zero-dimensional (lumped parameter) and one dimensional models, Department of Cardiovascular Science, Faculty of Medicine, based on simplified representations of the components of the cardiovascular system, Dentistry and Health, University of can contribute strongly to our understanding of circulatory physiology. Zero-D Sheffield, Sheffield S10 2RX, UK models provide a concise way to evaluate the haemodynamic interactions among the cardiovascular organs, whilst one-D (distributed parameter) models add the facility to represent efficiently the effects of pulse wave transmission in the arterial network at greatly reduced computational expense compared to higher dimensional computational fluid dynamics studies. There is extensive literature on both types of models. Method and Results: The purpose of this review article is to summarise published 0D and 1D models of the cardiovascular system, to explore their limitations and range of application, and to provide an indication of the physiological phenomena that can be included in these representations. The review on 0D models collects