原创力文档salivary ph as a marker of plasma adiponectin concentrations in women唾液ph值作为一个女性血浆脂联素浓度的标志.pdfVIP
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salivary ph as a marker of plasma adiponectin concentrations in women唾液ph值作为一个女性血浆脂联素浓度的标志
Tremblay et al. Diabetology Metabolic Syndrome 2012, 4:4
DIABETOLOGY
/content/4/1/4
METABOLIC SYNDROME
RESEARCH Open Access
Salivary pH as a Marker of Plasma Adiponectin
Concentrations in Women
*
Monique Tremblay, Yacine Loucif, Julie Methot, Diane Brisson and Daniel Gaudet
Abstract
Background: Plasma adiponectin is a significant correlate of the pro-inflammatory cardiometabolic risk profile
associated with obesity and type 2 diabetes. Salivary pH is influenced by several cardiometabolic risk components
such as inflammation, oxidation and numerous oral and systemic health modulators, including the menopausal
status. This study aimed to assess the association between plasma adiponectin concentrations and salivary pH in
women according to the menopausal status.
Method: Unstimulated saliva collection was performed in 151 Caucasian women of French-Canadian origin (53
premenopausal women (PMW) and 98 menopausal women (MW)). Student’s t test, ANOVA and linear regression
models were used to assess the association between plasma adiponectin concentrations and salivary pH.
Results: Plasma adiponectin levels increased as a function of salivary pH in the whole sample and among MW (r = 0.29
and r = 0.36, p 0.001). The proportion of the variance of plasma adiponectin levels explained by the salivary pH (R2)
was 10.8% (p 0.001). Plasma adiponectin levels progressively increased across salivary pH quartiles (p = 0.005).
Conclusions: These results suggest that salivary pH is a significant correlate of plasma adip
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