scopararanes c–g new oxygenated pimarane diterpenes from the marine sediment-derived fungus eutypella scoparia fs26scopararanes c g新含氧pimarane二萜的海洋sediment-derived真菌eutypella scoparia fs26.pdfVIP

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scopararanes c–g new oxygenated pimarane diterpenes from the marine sediment-derived fungus eutypella scoparia fs26scopararanes c g新含氧pimarane二萜的海洋sediment-derived真菌eutypella scoparia fs26.pdf

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scopararanes c–g new oxygenated pimarane diterpenes from the marine sediment-derived fungus eutypella scoparia fs26scopararanes c g新含氧pimarane二萜的海洋sediment-derived真菌eutypella scoparia fs26

Mar. Drugs 2012, 10, 539-550; doi:10.3390/m OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article Scopararanes C–G: New Oxygenated Pimarane Diterpenes from the Marine Sediment-Derived Fungus Eutypella scoparia FS26 Li Sun 1,2, Dongli Li 1, Meihua Tao 1, Yuchan Chen 1, Feijun Dan 2 and Weimin Zhang 1,* 1 Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Provincial Open Laboratory of Applied Microbiology, State Key Laboratory of Applied Microbiology (Ministry-Guangdong Province Jointly Breeding Base), South China, Guangdong Institute of Microbiology, Guangzhou 510070, China; E-Mails: sunli525525525@ (L.S.); yichen802003@ (D.L.); taomeihua@ (M.T.); yuchan2006@126.com (Y.C.) 2 College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, China; E-Mail: danfj0458@ * Author to whom correspondence should be addressed; E-Mail: wmzhang58@; Tel.: +86-20 Fax: +86-20 Received: 29 November 2011; in revised form: 16 February 2012 / Accepted: 20 February 2012 / Published: 27 February 2012 Abstract: Five new oxygenated pimarane diterpenes, named scopararanes C–G (1–5) were isolated from the culture of a marine sediment-derived fungus Eutypella scoparia FS26 obtained from the South China Sea. The structures of these compounds were established on the basis of extensive spectroscopic analysis. The absolute configurations of compounds 1–5, were determined by CD spectroscopic analysis and comparison with literature d