原创力文档search for age-dependent as compared to mutagen-induced mutations on the x-chromosome affecting viability in drosophila melanogaster males寻找年龄相关性相比mutagen-induced突变x染色体上,影响果蝇雄性的可行性.pdfVIP
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search for age-dependent as compared to mutagen-induced mutations on the x-chromosome affecting viability in drosophila melanogaster males寻找年龄相关性相比mutagen-induced突变x染色体上,影响果蝇雄性的可行性
Search for age-dependent as compared to mutagen-induced
mutations on the X-chromosome affecting viability
in Drosophila melanogaster males
T. BJÖRKLUND, G. ENGSTRÖM, Trudy McKAY L.E. LILJEDAHL
Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics,
Box 7023, 750 07 Uppsala, Sweden
* Institute of Animal Genetics, King’s Buildings, West Mains Road,
Edinburgh EH9 3JN, United Kingdom
Summary
The effect of ageing on the possible accumulation of deleterious genetic changes compared to
ethyl methane sulfonate (EMS) induced mutations on the X-chromosome in gametes was investiga-
ted in a laboratory population of Drosophila melanogaster males. To detect X-linked mutations
affecting viability, differences in sex ratio (number of male offspring/number of female offspring)
were measured in the of these males taken at three different or after EMS
progeny ages,
and mated to attached-X females. There were no differences in sex ratio for
exposure, significant
the three age periods but a strong significant difference in sexratio after EMS exposure was
obtained. This indicates that no accumulation of mutations takes in the
age-dependent place germ
cells.
Key words :ageing, mutagen (ethyl methane sulfonate) exposure, mutations, X-chromosome,
Drosophila melanogaster.
Résumé
Recherche sur le chromosome X de mutations dép
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