spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia中心体的自身抗体在儿童水痘和post-varicella急性小脑性共济失调.pdfVIP

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spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia中心体的自身抗体在儿童水痘和post-varicella急性小脑性共济失调.pdf

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spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia中心体的自身抗体在儿童水痘和post-varicella急性小脑性共济失调

BMC Pediatrics BioMed Central Research article Open Access Spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia 1 2 1 2 Marvin J Fritzler* , Meifeng Zhang , Laura M Stinton and Jerome B Rattner Address: 1Department of Medicine, Faculty of Medicine University of Calgary, 3330 Hospital Dr. NW, Calgary, AB T2N 4N1, Canada and 2Department of Cell Biology Anatomy, Faculty of Medicine University of Calgary, 3330 Hospital Dr. NW, Calgary, AB T2N 4N1, Canada Email: Marvin J Fritzler* - fritzler@ucalgary.ca; Meifeng Zhang - mzhan@ucalgary.ca; Laura M Stinton - lmstinto@ucalgary.ca; Jerome B Rattner - rattner@ucalgary.ca * Corresponding author Published: 23 September 2003 Received: 26 June 2003 Accepted: 23 September 2003 BMC Pediatrics 2003, 3:11 This article is available from: /1471-2431/3/11 © 2003 Fritzler et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: Sera from children with post-varicella infections have autoantibodies that react with centrosomes in brain and tissue culture cells. We investigated the sera of children with infections and post-varicella ataxia and related conditions for reactivity to five recombinant