spontaneous closure of macular holes secondary to posterior uveitis case series and a literature review自发黄斑孔二次关闭后葡萄膜炎病例系列和文献综述.pdfVIP

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spontaneous closure of macular holes secondary to posterior uveitis case series and a literature review自发黄斑孔二次关闭后葡萄膜炎病例系列和文献综述.pdf

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spontaneous closure of macular holes secondary to posterior uveitis case series and a literature review自发黄斑孔二次关闭后葡萄膜炎病例系列和文献综述

Bonnin et al. Journal of Ophthalmic Inflammation and Infection 2013, 3:34 /content/3/1/34 REVIEW Open Access Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review 1* 2 2 2 2 2 Nicolas Bonnin , Pierre-Loïc Cornut , Florian Chaise , Elodie Labeille , Helene Janin Manificat , Audrey Feldman , 3 1 1 2 Laurent Perard , Franck Bacin , Frédéric Chiambaretta and Carole Burillon Abstract The occurrence of a macular hole due to posterior uveitis is infrequently reported. We report the evolution of three cases of macular holes secondary to posterior segment inflammation. A complete inflammatory and infectious assessment found one case of toxocariasis, one of sarcoidosis, and one of syphilis. After medical etiological treatment, macular hole closure was rapidly obtained in all the cases and confirmed by spectral domain optic coherence tomography, with visual acuity improvement. Fibrous scarring developed in two cases, and foveal photoreceptor complex normalization was observed in the sarcoidosis case. These observations demonstrate that macular holes secondary to posterior uveitis frequently resolve without surgical intervention and so could be underdiagnosed if the patient is not evaluated at the time of onset before spontaneous hole closure. Keywords: Posterior uveitis, Macular hole, Toxocara canis, Sarcoidosis, Syphilis Review 20/40 in his right eye and counting fingers in his left Introduction eye. Full examinat