supercritical carbon dioxide extraction of the oak silkworm (antheraea pernyi) pupal oil process optimization and composition determination柞蚕的超临界二氧化碳萃取(antheraea pernyi)蛹油流程优化和组合的决心.pdfVIP
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supercritical carbon dioxide extraction of the oak silkworm (antheraea pernyi) pupal oil process optimization and composition determination柞蚕的超临界二氧化碳萃取(antheraea pernyi)蛹油流程优化和组合的决心
Int. J. Mol. Sci. 2012, 13, 2354-2367; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
Supercritical Carbon Dioxide Extraction of the Oak Silkworm
(Antheraea pernyi) Pupal Oil: Process Optimization and
Composition Determination
Wen-Juan Pan 1, Ai-Mei Liao 1,2, Jian-Guo Zhang 1, Zeng Dong 1 and Zhao-Jun Wei 1,*
1 School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009,
China; E-Mails: wenjuanpan12345@163.com (W.-J.P.); liaoaimei100@163.com (A.-M.L.);
zjghfut@ (J.-G.Z.); dongozeng@163.com (Z.D.)
2 Department of Life Science, Hefei Normal University, Hefei 230061, China
* Author to whom correspondence should be addressed; E-Mail: zjwei@;
Tel.: +86-551-2919369; Fax: +86-551-2919369.
Received: 22 November 2011; in revised form: 19 January 2012 / Accepted: 13 February 2012 /
Published: 21 February 2012
Abstract: Supercritical carbon dioxide (SC-CO ) extraction of oil from oak silkworm
2
pupae was performed in the present research. Response surface methodology (RSM) was
applied to optimize the parameters of SC-CO2 extraction, including extraction pressure,
temperature, time and CO2 flow rate on the yield of oak silkworm pupal oil (OSPO). The
optimal extraction condition for oil yield within the experimental range of the variables
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