原创力文档tailoring the process of informed consent in genetic and genomic research裁剪基因和基因组研究的知情同意的过程.pdfVIP
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tailoring the process of informed consent in genetic and genomic research裁剪基因和基因组研究的知情同意的过程
Rotimi and Marshall Genome Medicine 2010, 2:20
/content/2/3/20
CO M M E N TA R Y
Tailoring the process of informed consent in
genetic and genomic research
1 2
Charles N Rotimi* and Patricia A Marshall*
Introduction
Abstract
Advances in genomic technology and computational
Genomic science and associated technologies are approaches have significantly changed our understanding
facilitating an unprecedented rate of discovery of of the non-random distribution of human genetic variants
novel insights into the relationship between human and its impact on disease susceptibility and variable drug
genetic variation and health. The willingness of large response across human populations. A critical element of
numbers of individuals from dierent ethnic and this success story has been the availability of large cohorts
cultural backgrounds to donate biological samples of unrelated individuals and families willing to donate
is one of the major factors behind the success of tissue and blood samples for genetic and biochemical
the ongoing genomic revolution. Although current analysis. Increasingly, genomic studies are being con-
informed consent documents and processes ducted among people from diverse cultural, linguistic and
demonstrate a commitment to ensuring that study socio-economic backgrounds throughout the world. e
participants are well informed of the risks and global expansion of genomic research, comb
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