原创力文档tentative mapping of transcription-induced interchromosomal interaction using chimeric est and mrna data初步的映射transcription-induced染色体间交互使用嵌合est和mrna数据.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
tentative mapping of transcription-induced interchromosomal interaction using chimeric est and mrna data初步的映射transcription-induced染色体间交互使用嵌合est和mrna数据
Tentative Mapping of Transcription-Induced
Interchromosomal Interaction using Chimeric EST and
mRNA Data
Per Unneberg*, Jean-Michel Claverie
Structural and Genomic Information Laboratory, Centre National de la Recherche Scientifique (CNRS) UPR-2589, Institut de Biologie Structurale et
Microbiologie, Marseille, France
Recent studies on chromosome conformation show that chromosomes colocalize in the nucleus, bringing together active
genes in transcription factories. This spatial proximity of actively transcribing genes could provide a means for RNA interaction
at the transcript level. We have screened public databases for chimeric EST and mRNA sequences with the intent of mapping
transcription-induced interchromosomal interactions. We suggest that chimeric transcripts may be the result of close
encounters of active genes, either as functional products or ‘‘noise’’ in the transcription process, and that they could be used as
probes for chromosome interactions. We have found a total of 5,614 chimeric ESTs and 587 chimeric mRNAs that meet our
selection criteria. Due to their higher quality, the mRNA findings are of particular interest and we hope that they may serve as
food for thought for specialists in diverse areas of molecular biology.
Citation: Unneberg P, Claverie J-M (2007) Tentative Mapping of Transcription-Induced Interchromosomal Interaction using Chimeric EST and mRNA
Data. PLoS ONE 2(2): e254. doi:10.1371/journal.pone.0000254
INTRODUCTION fact, the chromosome is now known to be a highly mobile
With the development of increasingly sophisticated large-scale structure, with territories intermingling significantly in the nucleus
sequencing and microarray techniques, the known transcriptome [16].
continues to grow. Even though the idea that one gene produces
您可能关注的文档
- synthesis, molecular structure and characterization of allylic derivatives of 6-amino-3-methyl-1,2,4-triazolo[3,4-f][1,2,4]-triazin-8(7h)-one烯丙基的衍生物的合成、分子结构及进一步表征6-amino-3-methyl-1,2,4-triazolo[3、4 f][1、2、4]-triazin-8u2014u2014(7 h).pdf
- synthesis, molecular structure, spectral properties and antifungal activity of polymethylene-α,ω-bis(n,n- dimethyl-n-dodecyloammonium bromides)合成、分子结构、光谱特性和抗真菌活性polymethylene-α,ω-bis(n,n - dimethyl-n-dodecyloammonium陈词滥调).pdf
- synthesis, molecular structure and reactivity of 5-methylidene-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolines5-methylidene-1的合成、分子结构及反应,2,3,5-tetrahydroimidazo[2,1 b]喹唑啉.pdf
- synthesis, multinuclear nmr characterization and dynamic property of organic–inorganic hybrid electrolyte membrane based on alkoxysilane and poly(oxyalkylene) diamine合成、多核的核磁共振特性和动态特性的有机-无机杂化基于alkoxysilane电解质膜和聚氧化烯二胺.pdf
- synthesis, nmr and crystallographic studies of 2-substituted dihydroquinazolinones derived from (s)-phenylethylamine合成、核磁共振以及晶体的研究2-substituted dihydroquinazolinones来自(s)苯乙胺.pdf
- synthesis, properties characterization and applications of various organobismuth compounds各种organobismuth化合物的合成、性能表征和应用程序.pdf
- synthesis, reactions and antimicrobial activities of 8-ethoxycoumarin derivatives的合成、反应和抗菌活动8-ethoxycoumarin衍生品.pdf
- synthesis, reactions and biological evaluation of some new naphtho[2,1-b]furan derivatives bearing a pyrazole nucleus的合成、反应和生物评价一些新的naphtho(2,1 b)呋喃衍生物轴承一个吡唑核.pdf
- synthesis, spectral and antibacterial studies of copper(ii) tetraaza macrocyclic complexes的合成、光谱和抗菌研究铜(ii)tetraaza大环配合物.pdf
- synthesis, singlet oxygen photogeneration and dna photocleavage of porphyrins with nitrogen heterocycle tails卟啉的合成、单线态氧photogeneration和dna photocleavage与氮杂环的尾巴.pdf
- tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation腱覆盖所需的基底膜上皮细胞保留和预防粘连的形成.pdf
- tensor decomposition reveals concurrent evolutionary convergences and divergences and correlations with structural motifs in ribosomal rna张量分解显示并行进化和相关性的共同点和不同点在核糖体rna结构图案.pdf
- ten-week lifestyle changing program reduces several indicators for metabolic syndrome in overweight adults十周的生活方式改变程序减少了几个指标在超重的成年人代谢综合征.pdf
- terahertz active photonic crystals for condensed gas sensing光子晶体太赫兹活跃冷凝气体传感.pdf
- terminal investment individual reproduction of ant queens increases with age终端投资个体繁殖蚁女王随着年龄的增加.pdf
- terminal continuation (tc) rna amplification enables expression profiling using minute rna input obtained from mouse brain终端延续(tc)rna扩增使表达式分析使用微小rna输入来自老鼠的大脑.pdf
- termite resistance of mdf panels treated with various boron compounds抗白蚁的mdf板处理各种硼化合物.pdf
- termite resistant properties of sisal fiberboards防白蚁剑麻纤维板的属性.pdf
- tenomodulin inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathytenomodulin抑制视网膜新生血管形成的小鼠模型oxygen-induced视网膜病变.pdf
- terminalia catappa exerts antimetastatic effects on hepatocellular carcinoma through transcriptional inhibition of matrix metalloproteinase-9 by modulating nf-κb and ap-1 activity英文论文.pdf
文档评论（0）