testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial rationale, design, and methods测试简短干预的影响在初级保健问题药品使用随机对照试验原理,设计和方法.pdfVIP

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testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial rationale, design, and methods测试简短干预的影响在初级保健问题药品使用随机对照试验原理,设计和方法.pdf

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testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial rationale, design, and methods测试简短干预的影响在初级保健问题药品使用随机对照试验原理,设计和方法

Krupski et al. Addiction Science Clinical Practice 2012, 7:27 /content/7/1/27 STUDY PROTOCOL Open Access Testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial: rationale, design, and methods 1* 1 1 1,2 1 1 Antoinette Krupski , Jutta M Joesch , Chris Dunn , Dennis Donovan , Kristin Bumgardner , Sarah Peregrine Lord , Richard Ries1 and Peter Roy-Byrne1 Abstract Background: A substantial body of research has established the effectiveness of brief interventions for problem alcohol use. Following these studies, national dissemination projects of screening, brief intervention (BI), and referral to treatment (SBIRT) for alcohol and drugs have been implemented on a widespread scale in multiple states despite little existing evidence for the impact of BI on drug use for non-treatment seekers. This article describes the design of a study testing the impact of SBIRT on individuals with drug problems, its contributions to the existing literature, and its potential to inform drug policy. Methods/design: The study is a randomized controlled trial of an SBIRT intervention carried out in a primary care setting within a safety net system of care. Approximately 1,000 individuals presenting for scheduled medical care at one of seven designated primary care clinics who endorse problematic drug use when screened are randomized in a 1:1 ratio to BI versus enhanced care as usual (ECAU). Individuals in both groups are reassessed at 3, 6, 9, and 12 months after baseline. Self-reported drug use and other psychosocial measures collected at each data point are supplemented by urine analysis and public health-related data from adminis