the antisocial person an insight in to biology, classification and current evidence on treatmentu201c反社会u201d的人的洞察力生物学、分类和治疗目前的证据.pdfVIP
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the antisocial person an insight in to biology, classification and current evidence on treatmentu201c反社会u201d的人的洞察力生物学、分类和治疗目前的证据
Rodrigo et al. Annals of Gene ral Psychiatry 2010, 9:31
/content/9/1/31
R E V I E W Open Access
Review
The antisocial person: an insight in to biology,
classification and current evidence on treatment
1 2 1
Chaturaka Rodrigo* , Senaka Rajapakse and Gamini Jayananda
Abstract
Background: This review analyses and summar ises the recent advances in understanding the neurobiology of
violence and empathy, taxonomical issues on defining personality disorders characterised by disregard for social
norms, evidence for efficacy of different treatment modalities and ethical implications in defining at-risk individuals for
preventive interventions.
Methods: PubMed was searched with the keywords antisocial personality disorder, dissocial personality disorder and
psychopathy. The search was limited to articles published in English over the last 10 years (1999 to 2009)
Results: Both diagnostic manuals used in modern psychiatry, the Diagnostic and Statistical Manual published by the
American Psychiatric Association and the International Classification of Diseases published by the World Health
Organization, identify a personality disorder sharing similar traits. It is termed antisocial personality disorder in the
diagnostic and statistical manual and dissocial personality disorder in the International Classification of Diseases.
However, some authors query the ability of the existing manuals to identify a special category termed psychopathy,
which in their opinion deserves special attention. On treatment-related issues, many psychological and behavioural
therapies have shown success rates ranging from 25% to 62% in different cohorts. Multisystemic therapy and cognitive
behaviour therapy have been proven efficacious in many trials. There is
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