原创力文档the effect of temozolomidepoly(lactide-co-glycolide) (plga)nano-hydroxyapatite microspheres on glioma u87 cells behaviortemozolomidepoly的影响(lactide-co-glycolide)(plga)nano-hydroxyapatite微球对神经胶质瘤u87细胞行为.pdfVIP
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the effect of temozolomidepoly(lactide-co-glycolide) (plga)nano-hydroxyapatite microspheres on glioma u87 cells behaviortemozolomidepoly的影响(lactide-co-glycolide)(plga)nano-hydroxyapatite微球对神经胶质瘤u87细胞行为
Int. J. Mol. Sci. 2012, 13, 1109-1125; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
The Effect of Temozolomide/Poly(lactide-co-glycolide)
(PLGA)/Nano-Hydroxyapatite Microspheres on Glioma U87
Cells Behavior
1,† 2,† 2, 2 1 1,
Dongyong Zhang , Ang Tian , Xiangxin Xue *, Mei Wang , Bo Qiu and Anhua Wu *
1 Departments of Neurosurgery, The First Affiliated Hospital of China Medical University,
155 Nanjingbei Street, Heping District, Shenyang 110001, China;
E-Mails: dongyong0622@ (D.Z.); fhxue2002@ (B.Q.)
2 School of Materials and Metallurgy, Northeastern University, No.11, Lane 3, WenHua Road, HePing
District, Shenyang 110819, China; E-Mails: Ibrahimovic1002@126.com (A.T.);
wmei1010@ (M.W.)
† These authors contributed equally to this work.
* Authors to whom correspondence should be addressed; E-Mails: xuexx@ (X.X.);
wuanhua@ (A.W.); Tel.: +86-0-24(X.X.); +86-0-24(A.W.);
Fax: +86-0-24(X.X.); +86-0-24(A.W.).
Received: 7 November 2011; in revised form: 20 December 2011 / Accepted: 11 January 2012 /
Published: 19 January 2012
Abstract: In this study, we investigated the effects of temozolomide (TMZ)/Poly
(lactide-co-glycolide)(PLGA)/nano-hydroxyapatite microspheres on the behavior of U87
glioma cells. The micro
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