urinary c-peptide of insulin as a non-invasive marker of nutritional status some practicalities尿c -肽胰岛素作为营养状况的非侵入性标记一些实用性.pdfVIP
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urinary c-peptide of insulin as a non-invasive marker of nutritional status some practicalities尿c -肽胰岛素作为营养状况的非侵入性标记一些实用性
Urinary C-Peptide of Insulin as a Non-Invasive Marker of
Nutritional Status: Some Practicalities
1,2 ´ 1,3 1,3 4
James P. Higham *, Cedric Girard-Buttoz , Antje Engelhardt , Michael Heistermann
¨
1Junior Research Group Primate Sexual Selection, Reproductive Biology Unit, German Primate Centre, Gottingen, Lower Saxony, Germany, 2 Institute for Mind and
¨
Biology, University of Chicago, Chicago, Illinois, United States of America, 3 Courant Research Centre Evolution of Social Behaviour, Georg-August University, Gottingen,
¨
Lower Saxony, Germany, 4 Reproductive Biology Unit, German Primate Centre, Gottingen, Lower Saxony, Germany
Abstract
Nutritional status is a critical element of many aspects of animal ecology, but has proven difficult to measure non-invasively
in studies of free-ranging animals. Urinary C-peptide of insulin (UCP), a small polypeptide cleaved in an equimolar ratio from
proinsulin when the body converts it to insulin, offers great promise in this regard, and recent studies of several non-human
primate species have utilized it with encouraging results. Despite this, there are a number of unresolved issues related to
the collection, processing, storage and transport of samples. These include: contamination of samples on collection (most
commonly by dirt or faeces), short-term storage before returning to a field station, differences in processing and long-ter
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