原创力文档using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration使用数据,以确定遗传变异和环境危险因素年龄相关性黄斑变性的高危个体.pdfVIP
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using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration使用数据,以确定遗传变异和环境危险因素年龄相关性黄斑变性的高危个体
Using Genetic Variation and Environmental Risk Factor
Data to Identify Individuals at High Risk for Age-Related
Macular Degeneration
1 1 1 2 3
Kylee L. Spencer *, Lana M. Olson , Nathalie Schnetz-Boutaud , Paul Gallins , Anita Agarwal ,
4 5,6 7 8
Alessandro Iannaccone , Stephen B. Kritchevsky , Melissa Garcia , Michael A. Nalls , Anne B.
9 2 2 1
Newman , William K. Scott , Margaret A. Pericak-Vance , Jonathan L. Haines
1 Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America, 2 John P. Hussman Institute for Human Genomics, Miller
School of Medicine, University of Miami, Miami, Florida, United States of America, 3 Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee,
United States of America, 4 Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, 5 Department of
Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, 6 Sticht Center on Aging, Wake Forest University,
Winston-Salem, North Carolina, United States of America, 7 Laboratory for Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland,
United States of America, 8 Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America, 9 Department of Epidemiology,
University of Pittsburgh, Pittsburgh, Pennsylvania
Abstract
A major goal of personalized
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