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vegf promotes malaria-associated acute lung injury in micevegf促进特征在小鼠急性肺损伤
VEGF Promotes Malaria-Associated Acute Lung Injury in
Mice
1,2.¤ 1,2. 1,2. 1 1
Sabrina Epiphanio , Marta G. Campos , Ana Pamplona , Daniel Carapau , Ana C. Pena , Ricardo
´ 1 3 ´ 3 4 5 ´ 2,6
Ataıde , Carla A. A. Monteiro , Nuno Felix , Artur Costa-Silva , Claudio R. F. Marinho , Sergio Dias ,
Maria M. Mota1,2*
´ ˆ
1 Unidade de Malaria, Instituto de Medicina Molecular, Universidade de Lisboa, Lisboa, Portugal, 2 Instituto Gulbenkian de Ciencia, Oeiras, Portugal, 3 Faculdade de
´ ´ ´
Medicina Veterinaria de Lisboa, Universidade Tecnica de Lisboa, Portugal, 4 Servic¸o de Anatomia Patologica, Hospital de Santa Maria e Faculdade de Medicina de Lisboa,
˜ ˜ ˜
Portugal, 5 Departamento de Parasitologia, Universidade de Sao Paulo, Sao Paulo, Brasil, 6 Angiogenesis Laboratory, Centro Investigac¸ao em Patobiologia Molecular,
ˆ
Instituto Portugues de Oncologia Francisco Gentil, Centro Regional de Oncologia de Lisboa, Lisboa, Portugal
Abstract
The spectrum of the clinical presentation and severity of malaria infections is broad, ranging from uncomplicated febrile
illness to severe forms of disease such as cerebral ma
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