voltammetric determination of acetaminophen in the presence of codeine and ascorbic acid at layer-by-layer mwcnthydroquinone sulfonic acid-overoxidized polypyrrole modified glassy carbon electrode英文论文.pdfVIP

SAGE-Hindawi Access to Research International Journal of Electrochemistry Volume 2011, Article ID 764294, 10 pages doi:10.4061/2011/764294 Research Article Voltammetric Determination of Acetaminophen in the Presence of Codeine and Ascorbic Acid at Layer-by-Layer MWCNT/Hydroquinone Sulfonic Acid-Overoxidized Polypyrrole Modified Glassy Carbon Electrode Saeed Shahrokhian1, 2 and Reyhaneh-Sadat Saberi1 1 Department of Chemistry, Sharif University of Technology, Tehran 11155-9516, Iran 2 Institute for Nanoscience and Technology, Sharif University of Technology, Tehran 11155-9516, Iran Correspondence should be addressed to Saeed Shahrokhian, shahrokhian@ Received 26 March 2011; Revised 19 May 2011; Accepted 21 May 2011 Academic Editor: Farnoush Faridbod Copyright © 2011 S. Shahrokhian and R.-S. Saberi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. A very sensitive electrochemical sensor constructed of a glassy carbon electrode modified with a layer-by-layer MWCNT/doped- overoxidized polypyrrole (oppy/MWCNT /GCE) was used for the determination of acetaminophen (AC) in the presence of codeine and ascorbic acid (AA). In comparison to the bare glassy carbon electrode, a considerable shift in the peak potential together with an increase in the peak current was observed for AC on the surface of oppy/MWCNT/GCE, which can be related to the enlarged microscopic surface area of the electrode. The effect of the experimental conditions on the electrode response, such as types of counter ion, pyrrole and counter ion concentration, potential and number of cycles in the polymerization procedure, amount of MWCNT,