原创力文档bluetongue virus vp1 polymerase activity in vitro template dependency, dinucleotide priming and cap dependency蓝舌病病毒vp1聚合酶活性在体外模板依赖性,二核苷酸启动和帽的依赖.pdfVIP
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bluetongue virus vp1 polymerase activity in vitro template dependency, dinucleotide priming and cap dependency蓝舌病病毒vp1聚合酶活性在体外模板依赖性,二核苷酸启动和帽的依赖
Bluetongue Virus VP1 Polymerase Activity In Vitro:
Template Dependency, Dinucleotide Priming and Cap
Dependency
Eiko Matsuo, Polly Roy*
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
Abstract
Background: Bluetongue virus (BTV) protein, VP1, is known to possess an intrinsic polymerase function, unlike rotavirus VP1,
which requires the capsid protein VP2 for its catalytic activity. However, compared with the polymerases of other members
of the Reoviridae family, BTV VP1 has not been characterized in
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