c. elegans swan-1 binds to egl-9 and regulates hif-1-mediated resistance to the bacterial pathogen pseudomonas aeruginosa pao1秀丽隐杆线虫swan-1结合egl-9和调节hif-1-mediated抗绿脓假单胞菌pao1.pdfVIP

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1- Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1 Zhiyong Shao., Yi Zhang., Qi Ye, Jenifer Neeta Saldanha, Jo Anne Powell-Coffman* Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, United States of America Abstract Pseudomonas aeruginosa is a nearly ubiquitous human pathogen, and infections can be lethal to patients with impaired respiratory and immune systems. Prior studies have established that strong loss-of-function mutations in the egl-9 gene