ectopic expression of aid in a non-b cell line triggers a∶t and gc point mutations in non-replicating episomal vectors异位表达的援助non-b细胞系触发∶t和gc non-replicating游离向量的点突变.pdfVIP

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ectopic expression of aid in a non-b cell line triggers a∶t and gc point mutations in non-replicating episomal vectors异位表达的援助non-b细胞系触发∶t和gc non-replicating游离向量的点突变.pdf

ectopic expression of aid in a non-b cell line triggers a∶t and gc point mutations in non-replicating episomal vectors异位表达的援助non-b细胞系触发∶t和gc non-replicating游离向量的点突变

Ectopic Expression of AID in a Non-B Cell Line Triggers A:T and G:C Point Mutations in Non-Replicating Episomal Vectors ´ Tihana Jovanic, Benjamin Roche, Geraldine Attal-Bonnefoy, Olivier Leclercq, Franc¸ois Rougeon* ´ ´ ´ ´ ´ Unite de Genetique et Biochimie du Developpement, Departement d’Immunologie, URA CNRS 2581, Institut Pasteur, Paris, France Somatic hypermutation (SHM) of immunoglobulin genes is currently viewed as a two step process initiated by the deamination of deoxycytidine (C)

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