egf-induced emt and invasiveness in serous borderline ovarian tumor cells a possible step in the transition to low-grade serous carcinoma cellsegf-induced emt和侵袭性浆液性边缘卵巢肿瘤细胞可能一步过渡到低级的浆液性癌的细胞.pdfVIP
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egf-induced emt and invasiveness in serous borderline ovarian tumor cells a possible step in the transition to low-grade serous carcinoma cellsegf-induced emt和侵袭性浆液性边缘卵巢肿瘤细胞可能一步过渡到低级的浆液性癌的细胞
EGF-Induced EMT and Invasiveness in Serous Borderline
Ovarian Tumor Cells: A Possible Step in the Transition to
Low-Grade Serous Carcinoma Cells?
Jung-Chien Cheng, Nelly Auersperg, Peter C. K. Leung*
Department of Obstetrics and Gynecology, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
Abstract
In high-grade ovarian cancer cultures, it has been shown that epidermal growth factor (EGF) induces cell invasion by
activating an epithelial-mesenchymal transition (EMT). However, the effect of E
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