11肝衰（11 liver failure）.docVIP

11肝衰（11 liver failure） Four, Jane answer 1. why are liver dysfunction patients susceptible to infection? Answer: the liver is the major producer of immunoglobulins and complements, which can hold harmful antigenic substances from the gut. Kupffer cell phagocytic ability is very strong, can swallow foreign body in blood, bacteria and toxins, is a major barrier against bacterial and viral infections of the liver. When the liver due to a large number of liver parenchymal cell damage or necrosis and liver dysfunction, the anti infection effect weakened or disappeared and were susceptible to infection. 2. what is the difference between acute and chronic hepatic insufficiency? Answer: acute liver failure due to acute severe hepatitis, acute onset, serious disease, often appear jaundice, bleeding and coma symptoms; chronic liver dysfunction common disease because of cirrhosis and hepatocellular carcinoma, slow progression, long duration, often occurs in some action due to induced coma exacerbation. 3. patients with liver dysfunction, why is it easy to produce jaundice? Answer: the excretion of bilirubin and liver uptake of bilirubin, combined with the operation, excretion and extrahepatic (including extrahepatic biliary excretion and enterohepatic circulation and renal excretion) keep dynamic balance, if one or more links will lead to disorders, hyperbilirubinemia, clinical manifestations of jaundice. 4., liver dysfunction patients why bleeding? Answer: the liver is a variety of coagulation substances and anticoagulant substances generation and removal of the site, when the liver function seriously damaged, a variety of coagulation factor production decreased, coupled with the increase in anticoagulant substances in circulation, and therefore prone to bleeding 5. hepatic insufficiency hyperbilirubinemia on the body what harm? Answer: with high levels of bilirubin due to inhibition of oxidative phosphorylation to nerve cells, renal tubular epithelial cells prone to degenera