]全自动血凝仪检测原理及临床应用(Principle and clinical application of automatic blood coagulation analyzer).docVIP
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]全自动血凝仪检测原理及临床应用(Principle and clinical application of automatic blood coagulation analyzer)
]全自动血凝仪检测原理及临床应用(Principle and clinical application of automatic blood coagulation analyzer)
Principle and clinical application of automatic blood coagulation analyzer
With the development of medical science, timely diagnosis of bleeding and thrombotic diseases, clinical observation, analysis of anticoagulant dose seem more and more urgent, and the traditional manual methods and qualitative examination of single solidification cannot satisfy the clinical requirements, appearance and application of full automatic blood coagulation analyzer, the thrombosis and hemostasis become simple and accurate inspection of the project reliable, great to meet the needs of clinical diagnosis and treatment.
1 basic methods of detection
At present, blood coagulation apparatus mostly adopts biological methods, and can be divided into three kinds: current method, viscosity method and optical method.
One point one
Current method: this method is conductive with plasma samples of fibrin, inserted electrodes were broken, to determine whether fibrin formation using two current between the electrodes, and determine the solidification end point.
One point two
Viscosity method: also called immunomagnetic beads and detection part of the instrument is independent of the coil to produce the necessary fields, testing on the measured magnetic beads were added, the changes caused by the magnetic field of magnetic beads in motion, with plasma coagulation, plasma viscosity increased for small beads, swing gradually reduced, the electromagnetic sensor in the instrument, different volatility determination of small beads, the plasma coagulation time calculation.
One point three
Optical method: this method is the most frequently used method of blood coagulation test. When the plasma is gradually solidified in the sample cup, the fibrinogen changes into fibrin, and its physiological properties change as well. When a beam passes through the sample cup, the intensity of the transmitted light and astigmatism
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