the mechanics of metastasis insights from a computational model转移的见解的力学计算模型.pdfVIP

The Mechanics of Metastasis: Insights from a Computational Model G. Wayne Brodland*, Jim H. Veldhuis Department of Civil and Environmental Engineering, University of Waterloo, Waterloo, Ontario, Canada Abstract Although it may seem obvious that mechanical forces are required to drive metastatic cell movements, understanding of the mechanical aspects of metastasis has lagged far behind genetic and biochemical knowledge. The goal of this study is to learn about the mechanics of metastasis using a cell-based finite element model that prov