the role of atp and adenosine in the control of hepatic blood flow in the rabbit liver in vivo三磷酸腺苷和腺苷的作用的肝血流控制兔子体内肝脏.pdfVIP

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the role of atp and adenosine in the control of hepatic blood flow in the rabbit liver in vivo三磷酸腺苷和腺苷的作用的肝血流控制兔子体内肝脏.pdf

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the role of atp and adenosine in the control of hepatic blood flow in the rabbit liver in vivo三磷酸腺苷和腺苷的作用的肝血流控制兔子体内肝脏

Comparative Hepatology BioMed Central Research Open Access The role of ATP and adenosine in the control of hepatic blood flow in the rabbit liver in vivo 1 2 1 Dominic J Browse , Robert T Mathie , Irving S Benjamin and Barry Alexander*1 Address: 1Liver Sciences Unit, Academic Department of Surgery, GKT School of Medicine and Dentistry, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK and 2Division of Surgery, Imperial College School of Medicine, Hammersmith Hospital, 150 Du Cane Road, London W12 ONN, UK Email: Dominic J Browse - barry.alexander@kcl.ac.uk; Robert T Mathie - barry.alexander@kcl.ac.uk; Irving S Benjamin - irving.benjamin@kcl.ac.uk; Barry Alexander* - barry.alexander@kcl.ac.uk * Corresponding author Published: 26 November 2003 Received: 15 July 2003 Accepted: 26 November 2003 Comparative Hepatology 2003, 2:9 This article is available from: /content/2/1/9 © 2003 Browse et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: The role of adenosine and ATP in the regulation of hepatic arterial blood flow in the buffer response was studied in vitro and in a new in vivo model in the rabbit. The model achieves portal-systemic diversion by insertion of a silicone rubber prosthesis between the portal