the synovial proteome analysis of fibroblast-like synoviocytes的滑液蛋白质组分析呈synoviocytes.pdfVIP

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the synovial proteome analysis of fibroblast-like synoviocytes的滑液蛋白质组分析呈synoviocytes.pdf

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the synovial proteome analysis of fibroblast-like synoviocytes的滑液蛋白质组分析呈synoviocytes

Available online /content/6/2/R161 Research article Open Access The synovial proteome: analysis of fibroblast-like synoviocytes 1 2 1 1 2,3 Kumar Dasuri , Mihaela Antonovici , Keding Chen , Ken Wong , Kenneth Standing , Werner Ens2,3, Hani El-Gabalawy1 and John A Wilkins1,2,3 1Rheumatic Diseases Research Laboratory, University of Manitoba, Winnipeg, Canada 2Manitoba Centre for Proteomics, Department of Medicine, University of Manitoba, Winnipeg, Canada 3Time of Flight Laboratory, Department of Physics and Astronomy, University of Manitoba, Winnipeg, Canada Corresponding author: John A Wilkins, (e-mail: jwilkin@cc.umanitoba.ca) Received: 17 Dec 2003 Revisions requested: 13 Jan 2004 Revisions received: 13 Jan 2004 Accepted: 21 Jan 2004 Published: 16 Feb 2004 Arthritis Res Ther 2004, 6:R161-R168 (DOI 10.1186/ar1153) © 2004 Dasuri et al., licensee BioMed Central Ltd (Print ISSN 1478-6354; Online ISSN 1478-6362). This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract The present studies were initiated to determine the protein normal or pathological FLS function (e.g. uridine expression patterns of fibroblast-like synovial (FLS) cells diphosphoglucose dehydrogenase, galectin 1 and galectin 3) derived from the synovia of rheumatoid arthritis patients. The or that have been characterized as potential autoantigens