丹参通心络联用治疗冠心病疗效分析.docVIP

丹参通心络联用治疗冠心病疗效分析 　【关键词】 通心络胶囊 　　摘 要：目的：探讨丹参、通心络胶囊治疗冠心病的临床疗效及安全性。方法：58例冠心病患者随机分为治疗组和对照组，对照组静滴硝酸甘油，治疗组静滴复方丹参，口服通心络胶囊，观察临床症状，心电图，血液流变学等变化。结果：两组临床症状，心电图无显著差异性（Pgt;0.05），4周内进展为急性心肌梗塞对照组3例（10.71%），治疗组无发生，有统计学意义（P=0.0455），血液流变学有显著差异性(Plt;0.01或Plt;0.05)。结论：丹参、通心络胶囊联用无副作用，作用相加，具有扩张冠脉，降低血液粘度，抑制血小板等，改善临床症状，是治疗冠心病有效药物。 　　关键词： 冠心病； 丹 参； 通心络胶囊 　　Analyzing the Effect of Root of red-rooted Salvia Coadunited Tongxinluo Capsules on Coronary Heart Disease 　　　　Abstract： Objective: To discuss the clinical curative effect and safety of coronary heart disease who were treated with root of red-rooted salvia coadunited Tongxinluo capsules. Methods: We trabant dieretic 58 cases into therapeusis group and control group, the control group were infusion by intravenous drip nitroglycerin , the other were root of red-rooted salvia injection, oral Tongxinluo capsules,and then observed the clinical symptoms, the alleosis of electrocardiogram and hemorrheology. Results: Both of the groups have no difference significant on clinical symptoms and electrocardiogram(Pgt;0.05), 4 weeks later, 3 cases were strided acute myocardial infarction in control group(10.71%), the other didn?t generate. It has statistical sense(P=0.0455), and significant difference on hemorrheology(Plt;0.01 or Plt;0.05). Conclusion: It has no side effect if we treated with root of red-rooted salvia coadunited Tongxinluo capsules, both of them can distente coronary artery, debase the blood viscosity, inhibite thrombocyte, improve the clinical symptoms, they are useful for coronary heart disease treatment. 　　Key words: Coronary heart disease; Root of red-rooted salvia; Tongxinluo capsule 　　我院自2001年10月至2003年10月应用丹参、通心络治疗冠心病30例，获得较好的临床疗效，现报道如下： 　　1 资料和方法 　　1.1 临床资料：58例为我院住院病人，随机分成30例为复方丹参注射液，通心络胶囊治疗组，28例为对照组。治疗组30例，男25例，女5例，年龄49～84岁，平均年龄65岁。对照组28例，男24例，女4例，年龄50～82岁，平均年龄63岁。全部病例均符合1979年WHO制定的缺血性心脏病的命名和诊断标准，治疗组劳力性心绞痛20例，自发性心绞痛5例，无症状型冠心病２例，缺血性心肌病型冠心病2例，梗塞后心绞痛1例；对照组劳力性心绞痛18例，自发性心绞痛4例，无症状型冠心病3例，缺血性心肌病型冠心病2例，梗塞后心绞痛1例。 　　1.2 治疗方法：治疗组应用复方丹参注射