新通注射液治疗冠心病心绞痛疗效观察.docVIP

新通注射液治疗冠心病心绞痛疗效观察 　 作者：彭辉强　陈曼佳　刘卫平　黄林喜　吴贤仁 【关键词】 注射 　　摘要：目的：观察新通注射液治疗冠心病心绞痛的临床疗效。方法：160例冠心病心绞痛患者，按1：1的比例，随机分为两组。以新通注射液12ml加入5%葡萄糖液500ml静滴治疗为治疗组，以复方丹参针12ml加入5%葡萄糖液500ml静滴治疗为对照组，（有糖尿病者改用生理盐水稀释）。均每日一次，连续治疗2周，观察治疗前后心绞痛症状、心电图的变化。结果：心绞痛症状疗效：治疗组总有效率97.5%，对照组总有效率72.5%，两组比较有显著性差异（Plt;0.01）；心电图疗效：治疗组总有效率65.0%，对照组总有效率42.5%，两组比较有显著性差异（Plt;0.01）。结论：新通注射液治疗冠心病心绞痛疗效可靠，值得临床推广。 　　关键词：冠心病；心绞痛；新通注射液；疗效 　　Clinical Therapeutic Effect of Xin-tong Injection on Angina Pectoris 　　Abstract： Objective： To observe clinical effects of Xin-tong injection on patients with Angina Pectoris. Methods： In the proporion of one to one, 160 cases angina pectoris patients were randomly divided into treatment group and control group,80 cases of treatment group with Xin-tong Injection 12 ml +5%GS 500ml iv drip and 80 cases of control group with Dan-shen injection 12 ml +5%GS 500ml iv drip(0.9%NS was used in patients with DM), Every case was treated qd for two weeks. The symptom and EKG changes of angina pectoris were observed before and after treatment. Results： On symptom effect, the general effective rate of treatment group was 97.5%, and the general effective rate of control group was 72.5%, there was significant difference between them (Plt;0.01). On ECG change, the general effective rate of treatment group was 65.0%, and the general effective rate of control group was 42.5%, there was significant difference between them (Plt;0.01). Conclusion： The treatment effect of Xin-tong Injection on angina pectoris was credible, it was worthy of extending in clinical. 　　Key words：Coronary heart disease; Angina pectoris; Xin-tong Injection;Treatment effect 　　2002年1月至2005年1月，我院急诊科应用新通注射液治疗冠心病心绞痛患者80例，观察治疗前后临床症状、心电图变化，分析报告如下。 　　1 临床资料 　　1.1 病例选择：参照世界卫生组织的“缺血性心脏病的命名及诊断标准”的意见［1］，选择符合诊断的冠心病心绞痛患者160例，按1：1的比例随机分为治疗组和对照组各80例。治疗组男42例，女38例，年龄40～74岁，平均年龄（56.3±9.4）岁，病程4～36月，平均（6.4±1.0）个月，其中劳累性心绞痛48例，自发性心绞痛11例，混合性心绞痛21例。对照组男46例，女34例，年龄42～78岁，平均年龄（54.8±9.6）岁，病程5～38个月，平均（6.5±1.2）个月，其中劳累性心绞痛44例，自发性心绞痛12例，混合性心绞痛24例。两组患者在性别比例、年龄构