运脾固表法防治小儿反复呼吸道感染临床探究.docVIP

运脾固表法防治小儿反复呼吸道感染临床探究 　 作者：许双虹，胡小英，陈晓刚，刘华，陈治珍，赖东兰，李宜瑞，徐金燕 【摘要】 　　【目的】观察运脾固表法防治小儿反复呼吸道感染（ＲＲＴＩ）的临床疗效。【方法】采用简单随机法将60例患儿随机分为治疗组３０例和对照组３０例，治疗组给予具有运脾固表作用的复感宁方治疗（药物组成：五爪龙、太子参、茯苓、猴头菇、五叶参、薏苡仁、鸡内金、生甘草），对照组给予培菲康散治疗，两组均以１２周为１个疗程，并随访６个月，主要观察两组患儿治疗前后症状积分变化及临床疗效。【结果】治疗组在改善肺脾气虚症状及舌脉象积分方面显著优于对照组（Ｐ＜００１）；在临床疗效方面，治疗组总有效率为９０％，对照组为６０％，治疗组疗效优于对照组（Ｐ＜００５）。【结论】运脾固表法防治小儿反复呼吸道感染，不仅能有效地改善肺脾气虚的症状，还能缩短病程，减少呼吸道感染反复发作的频度与强度。 【关键词】 呼吸道感染／中药疗法；肺脾两虚／中药疗法；复感宁方／治疗应用；运脾固表；儿童 　　Abstract： ObjectiveTo observe the preventive and therapeutic effect of spleeninvigorating and superficiesconsolidating therapy for children recurrent respiratory tract infection (RRTI).MethodsSixty RRTI children were equally divided into two groups by simple randomization:the treatment group received Fugan Ning Prescription (FNP,mainly composed of Radix seu Folium Ipomoeae Cairicae,Radix Pseudostellariae,Poria,Carpophorum Hericii Erinacei,Radix Pentapanax leschenaultia,Semen Coisis,Endothelium Corneum Gigeriae Galli and Radix Glycyrrhizac),and the control group received bifid tripleviable.Twelve weeks constituted one treatment course,and a 6month followup was carried out.The therapeutic effect was evaluated and the changes of main symptoms scores were observed.ResultsThe effect on relieving symptoms of deficiency of lung and spleen in the treatment group was superior to that in the control group (P＜001),and the total effective rate on reducing attack frequency and severity of RRTI was 90% in the treatment group and 60% in the control group (P＜005).ConclusionSpleeninvigorating and superficiesconsolidating therapy is effective for the prevention and treatment of children recurrent respiratory tract infection through relieving the symptoms of 　　反复呼吸道感染（recurrent respiratory tract infection,RRTI）是指根据不同的年龄段，呼吸道感染每年发病在一定次数以上者。其临床特点为反复发作的上、下呼吸道感染，病程较长，部分患儿上感后可迅速发展为支气管炎或肺炎，少数则诱发哮喘。本课题组于２００６年１２月～２００８年５月，采用运脾固表法防治肺脾气虚型小儿ＲＲＴＩ ３０例，并与30例口服培菲康散治疗作比较，现将结果报道如下。 　　1临床资料 　　11小儿ＲＲＴＩ的诊断标准 　　参照１９８７年全国第一届小儿呼吸道疾病学术会议制定的ＲＲＴＩ诊断标准［１］：每年上呼吸道感染次数分别