试析灯盏花颗粒主要药效学试验(Analysis of the main pharmacodynamics experiments of Erigeron breviscapus granule).docVIP

试析灯盏花颗粒主要药效学试验(Analysis of the main pharmacodynamics experiments of Erigeron breviscapus granule).doc

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试析灯盏花颗粒主要药效学试验(Analysis of the main pharmacodynamics experiments of Erigeron breviscapus granule)

试析灯盏花颗粒主要药效学试验(Analysis of the main pharmacodynamics experiments of Erigeron breviscapus granule) Analysis of the main pharmacodynamics experiments of Erigeron breviscapus granule Date: 08, 25 [Abstract Objective two rat carotid blood flow velocity determination of flow meter ultrasonic probe (artery ligation of external carotid artery) to reflect the Yunnan plant pharmaceutical limited company to provide the breviscapine particle effect on cerebral blood flow; the Pursiness time of mice was observed, Erigeron breviscapus Granule on cerebral ischemia function. Method for the determination of effects of particles on platelet aggregation induced by AA, ADP and PAF in vivo of Born method; using electrical stimulation of rat carotid arterial thrombosis, inhibition function evaluation of Erigeron breviscapus Granule on thrombosis. Results Erigeron breviscapus pellets significantly increased cerebral blood flow and prolong mouse Pursiness time; Erigeron breviscapus pellets in vivo significantly inhibited AA and aggregation of ADP and PAF induced platelet and prolonged electrical stimulation of rat carotid artery thrombosis time. Conclusion Erigeron granule can increase the blood supply of brain tissue through the mechanism of anti platelet and anti thrombosis, which is very beneficial to the protection of ischemic brain tissue. Erigeron breviscapus granule, platelet aggregation, thrombosis, cerebral blood flow Pharmacokinetic, experiment, of, Erigeron, breviscapus, pellets Abstract Objective The arteria carotis externa [was ligated, and arteria carotis interna was kept opening The left carotid artery was exposed and placed over an ultrasonic flow probe. The brain flow volume was recorded with an ultrasonic volume meter. The Pursiness time of mice was observed to evaluate the effect of Erigeron breviscapus pellets on cerebral ischemia. Methods Born s method was used to investigate effects of Erigeron breviscapus pellets on rabbit platelet aggregation induced by adenosine d

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