医药生技产业发展现况及趋势.ppt

* * * * * * 醫藥生技產業的大趨勢（三） 若干生技藥品的專利即將過期。雖然大藥廠努力的在做技術阻擋（尤其是針對生技藥品的製造程序），學名藥的市場勢必擴大，競爭之激烈必然可期。 * More than 70 big drugs will lose their patent protection by 2011, causing a collective loss of $100 billion in annual sales. July 30, 2007, Business Week * 驢子拼勁 * 4個台灣人 * 台灣人在國際學名藥界站一席之地 * 用下圍棋思維布局未來五年 * 醫藥生技產業的大趨勢（四） 營養/保健食品， 預防及機能性之生技產品（Nutraceuticals）將會蓬勃發展。偽科學（Pseudo science）的理論與產品，雖已混入市場；但是，我們可預期更多的臨床數據會漸漸的公佈於世，有助於Nutraceuticals產業的推動與發展。 * Global Nutraceuticals Industry Hits $210 Billion and Then Some * Skin Care Market Skin care is a growth market Growth drivers Nearly 40% of the US population isolder than 45 Trends toward prevention and self-care Key products Anti-aging Cleansers Moisturizers Sun care Hand and body lotion Source: Packaged Facts, 2005 * 面膜 * 醫藥生技產業的大趨勢（五） 診斷與治療間之互動更形緊密。Pharmacogenomics將扮演主要角色。以「醫療資訊個人化」（Personalized, information-based approach）來治療病患將是個大趨勢。 「Theranostic era」（診斷／治療合而為一的時代）已經來臨，應用於癌症治療的領域尤為顯著。 * Today’s medicine challenge: One size doesn’t fit all * 藥物研發技術的演變 Natural Products Synthetics rDNA Genomics-Based Pharmacogenomics 1900-1940 1940-1970 1970-1990 1990-2010 2010- 非專一性(治療症狀) 系統化(減少醫療錯誤) 個人化(疾病預防) 技 術 改 革 現今的醫療 轉譯醫學 個人化醫療 第一代診斷試劑 數位影像、資訊整合、臨床基因體 資料來源：IMS Health、Deutsche Bank；生技中心ITIS計畫整理 The Promise of Personalized Medicine * ACCORDING TO ITS CHAMPIONS, PERSONALIZED MEDICINE CAN detect disease at an earlier stage, when it is easier to treat effectively enable the selection of optimal therapy reduce trial-and-error prescribing increase patient compliance with therapy improve the selection of targets for drug discovery reduce the time, cost and failure rate of clinical trials generate attractive returns without blockbuster-size sales revive drugs that failed clinical trials or were withdrawn from the market reduce development costs （due to shorter time to discovery） avoid withdrawal of marketed drugs reduce adverse drug reactions shift the emphasis in medicine from reaction to prevention