脊柱后路融合固定对不同月龄幼兔脊柱生长发育影响的实验研究.pdf

脊柱后路融合固定对不同月龄幼兔脊柱生长发育影响的实验研究.pdf

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英 文 摘 要 TheEffectiononSpinalGrowthandDevelopmentof DifferentMonthAgeRabbitwithDifferentRange PosteriorSpinalFusionandFixationin ExperimentalStudy ABSTRACT Objective:Thepurposeofthisstudyistoexplorethe eelectiononspinalgrowthanddevelopmentofdifferentmonth agerabbitwithdifferentrangespinalfusionandfixation,and offertheoreticalbasestotheselectionofspinalfusionrangein treatmentofscoliosis.Scoliosisisthecommondiseaseinspinal deformityofChildrenandteenagers,andthetreatmentalresult correlatecloselytothelawofspinalgrowth.Theclinical importanttopicandproblemisgraspthebestoccasionof treatment,andtacklereasonablycontradictionbetweenspinal fusionandspinalgrowth.Becauseofgrowthpotentialin Childrenandteenagersspine,sometimesalthoughobtaininga goodtreatmentalresultandfusion,deformitiesbecomemore severityafteroperationstepbystep,thisiscalledCrankshaft Phenomenon.Inthisstudy,animalmodelsimilartothepatient afteroperationofscoliosisbemade,posteriorfusionofdifferent rangeisproceedindifferentmonthagerabbits,withthepurpose ofobservingthechangesinrabbitsspine.Themain observationsinclude;grossappearance,lightmicroscope(HE sections),radiologicaloutcomes.Throughtheseobservations, 英 文 摘 要 themechanism ofcrankshaftphenomenonandtherelation betweenskeletonmaturiytor/andfusionrangeandcrankshaft phenomenoncanbeexplained,andtheinstructiontoselection ofoperativeoccasionandfusionrangeinclinicalcanbe analysed. Methods:48rabbitsweredividedinto2groups,24each namelygroupAandgroupB.TherabbitsingroupAwas6 weeksoldand15weeksoldingroupB.Eachgroupwas randomlydividedinto3subgroups,namelya,,a2,a3andb,,b2, b3.Threelumbarsegmentswerefusedandfixatedwithsteel wire勿 posteriortechniqueinsubgroupa,andb,,five segmentsinsubgroupa2andb2,sevensegmentsingroupa3and b3.Theallograftbonesrfomallogeneicrabbitsweregraftedto thespinousprocess,laminaofve

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