水 蛭（Leech）.docVIP

水 蛭（Leech） Leech -------------------------------------------------------------------------------- For leeches, Japanese leeches, Hirudo, Nipponia, Whitman, wide body golden thread, leech, Whitmania, pigra (Whitman), brown leech, Whitmania, acranulata (Whitman) and so on. Salty, Bitter, flat, poisonous. Liver entry and bladder meridian. Function: broken blood, remove blood stasis, dredging. Indications: blood stasis, amenorrhea, abdominal mass, accumulation, dry blood into tuberculosis, traumatic injury, pain, red eye nebula. For oral use: into the pill, Powder, 1.5 ~ 3G; torrefying grind swallow, every time 0.3 ~ 0.5g. External use: sucking at the sick place or dipping the drops. [modern research] Ingredients: mainly proteins. Also contains iron, manganese, zinc and other trace elements. The saliva of fresh leeches contains an anticoagulant substance called hirudin (Hirudin), belonging to polypeptides due to its molecular composition There is no tryptophan and arginine in it, so it has anticoagulant effect. But in dried herbs, hirudin has been destroyed. The saliva of the leech also contains histamine like substances, heparin and anti thromboxane, etc., and has synergistic effects with hirudin. Pharmacological action: 1. the action of blood, hirudin can prevent the action of thrombin on fibrin, and hinder blood coagulation. Hirudin is not heated or destroyed by ethanol. Leeches can secrete a histamine like substance, It can dilate capillaries and increase bleeding. The alcohol extract of leech blood coagulation inhibition effect than gadfly, insects, peach strong leech alcohol preparation effect than water preparation for strong. Hirudin 20mg can block 100g coagulation of human blood. The water extract of leech can inhibit the platelet aggregation induced by ADP, and can inhibit the aggregation of platelet in normal people, and has the effect of anti thrombosis. The results show that the leech has strong fibrinolytic activity in vitro, and its activity is significan