临床用药之安全用药篇（Safe use of drugs for clinical use）.docVIP

临床用药之安全用药篇（Safe use of drugs for clinical use） Safety medication for clinical use [I hope everyone will participate] Safe medication Safe medication should be done: According to the patients condition, the patients constitution and the overall situation of the medicine, the proper choice of drugs, and truly to the disease, and at the same time appropriate methods, appropriate dosage, appropriate time accurate medication. Note the contraindications, adverse reactions, interactions, etc. of the drug. And pay attention to spending as little money as possible. In this way, it can be safely, rationally, effectively and economically used. Careful use of gatifloxacin in diabetics Gatifloxacin is a commonly used third generation quinolone broad-spectrum antibacterial agent, which has a resistance to gram negative bacteria and gram positive aerobic, anaerobic and atypical bacteria, and is excreted by biotransformation. It is commonly used in pneumonia, chronic bronchitis, acute exacerbation, sinusitis and other respiratory tract infections and urinary tract infections. Data show that the incidence of hypoglycemia after gatifloxacin is 4 times higher than that of other antimicrobials, and that the risk of using the gatifloxacin is 17 times higher than that of other drugs. In the trial, 30 days after the use of antibiotics, abnormal glucose regulation is the highest of gatifloxacin (1.1%), followed by ciprofloxacin (0.3%), levofloxacin, moxifloxacin (0.3%) and the two generation cephalosporins was 0.2%, while the lowest macrolide, only 0.1%. Medical home although the mechanisms leading to abnormal blood glucose of gatifloxacin is unclear, but most of them think it is possible that the drug can promote the release of insulin hypoglycemia, and promote islet B cell vacuolization decreased insulin levels resulting in high blood glucose. In particular, it should be noted that in the trial, nearly 8% of the diabetic patients died after the admission of hypoglycemia, and 16.5% of the