四代头孢（Four generation cephalosporin）.docVIP

四代头孢（Four generation cephalosporin） (1) first generation cephalosporin; The commonly used medicine is cephalosporin, Cefradine, Cefradine, cefazolin and so on. The effect is positive for gram positive bacterial infections, including resistance to Staphylococcus aureus (MRSA) and penicillin resistant Neisseria gonorrhoeae. Oral cephalexin and cefadroxil and cephradine for mild to moderate respiratory tract infections (such as acute inflammation of the trachea and bronchi), urinary tract infection, skin and soft tissue infection, bone and joint infections in obstetrics and gynecology. Injection of cefazolin is widely used in severe infection and moderate infection sensitive bacteria. (2) cephalosporin of the second generation The commonly used drug cefamandole, cefuroxime, cefaclor, cefoxitin etc.. Effect of strong antibacterial effect against gram negative bacteria, gram positive bacteria and influenza bacillus (because of the second generation cephalosporins against gram negative and gram positive bacteria and other bacteria have antibacterial effect, so it is called broad-spectrum antibiotics). Commonly used in the treatment of Escherichia coli, Klebsiella, Proteus mirabilis, caused by Citrobacter, Haemophilus influenzae, Neisseria gonorrhoeae, meningococcal, Salmonella, Shigella and other respiratory tract, biliary tract, intestinal tract and soft tissue, bone and joint infections in obstetrics and gynecology. Application of more is more for oral cefuroxime, cefaclor. (3) cephalosporin of the third generation The commonly used medicine cefotaxime, cefoperazone, ceftriaxone, cefazolin. It has a strong antibacterial activity against gram - negative bacteria, anaerobic bacteria and gram - positive bacteria in severe, drug - resistant and even seriously life-threatening organisms. For sepsis, meningitis, pneumonia, osteomyelitis, pelvic infection and other serious infections and urinary tract infection, is the first choice for Escherichia coli and Klebsiella pneumonia