婴儿沙眼的衣原体肺炎-陶孝芬.pptVIP

* The bi-phasic chlamydial growth cycle involves transformation between two distinct forms: the elementary body (EB) and the reticulate body (RB). The metabolically inactive but highly infectious EB attaches to columnar epithelial cells and is internalized within a host cell membrane-bound phagosome?(A)?. During early stages of the life cycle, 1 to 10 hours post infection (hpi), the vesicle migrates to a perinuclear location near the Golgi apparatus(B)?. It is during this migration that the nascent phagocytic vesicle begins to be modified by Chlamydia-produced inclusion membrane proteins to fo