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European Journal of Radiology 85 (2016) 1993–2000
Contents lists available at ScienceDirect
European Journal of Radiology
j o u r na l h o m e p ag e: w w w. elsev /locate/ejr ad
Double contrast-enhanced ultrasonography in the detection of
periampullary cancer: Comparison with B-mode ultrasonography and
MR imaging
Zhang Ting a,b , Su Zhong-zhen b , Wang Ping b , Wu Tao b , Tang Wen c , Xu Er-jiao b ,
Ju Jin-xiu b , Quan Xian-yue a,∗ , Zheng Rong-qin b,∗∗
a Department of Medical Image Center, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
b Department of Medical Ultrasonics, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China
c Department of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China
a r t i c l e i n f o a b s t r a c t
Article history: Purpose: To investigate the value of double contrast-enhanced ultrasonography (DCEUS) in the detection
Received 26 July 2016 of periampullary cancer.
Accepted 26 August 2016 Materials and methods: Ninety-nine patients with surgery or biopsy-proven periampullary cancer who
underwent both DCEUS and magnetic resonance imaging (MRI) examinations before operation were
Keywords: enrolled in our study. DCEUS in which intravenous microbubbles were used in combination with oral
Periampullary cancer contrast agent and MRI were performed preoperatively to make a detection d
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