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ORIGINAL RESEARCH
Noncontrast MR Angiography (MRA) of
Infragenual Arteries Using Flow-Sensitive
Dephasing (FSD)-Prepared Steady-State
Free Precession (SSFP) at 3.0 Tesla:
Comparison with Contrast-Enhanced MRA
Nan Zhang, MD,1 Zhaoyang Fan, PHD,2 Nan Luo, MD,1 Xiaoming Bi, PHD,3
1 4 1 5
Yike Zhao, MD, Jing An, PHD, Jiayi Liu, MD, * Zhong Chen, PHD,
Zhanming Fan, PHD,1 and Debiao Li, PHD2
Background: To evaluate the feasibility and diagnostic performance of flow-sensitive dephasing (FSD)-prepared steady-
state free precession (SSFP) MR angiography (MRA) for imaging infragenual arteries at 3.0T, with contrast enhanced MR
angiography (CE MRA) as reference.
Methods: Twenty consecutive patients with suspicion of lower extremity arterial disease undergoing routine CE MRA
were recruited. FSD MRA was performed at calf before CE MRA. Image quality and stenosis degree of infragenual
arteries from both techniques were independently evaluated and compared. Six patients in this study underwent DSA
examination.
Results: Three undiagnostic segments were excluded with severe venous contamination in CE MRA. A total of 197 calf
arterial segments images were analyzed. No significant difference existed in the relative signal intensity (rSI) of arterial
segments between FSD MRA and CE MRA techniques (0.92 6 0.09 versus 0.93 60.05; P 50.207). However, the subjec-
tive image quality score was slightly higher in FSD MRA (3.66 60.81 versus 3.49 60.87; P 50.050). With CE MRA
images as reference standard, slight overestimation existed in FSD MRA (2.19 6 1.24 versus 2.09 6 1.18; P
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